Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

A compilation of brief news reports for Wednesday, August 18, 2010.

An unemployed, single mother from South Carolina has confessed to suffocating her two toddler children with her bare hands. After suffocating her one year-old and two year-old sons, 29 year-old Shaquan Duley drove her car into a river. Police have identified the suffocated children as Ja’van T. Duley and Devean C. Duley. She faces two murder charges and is scheduled to appear in court on Wednesday.

Duley had apparently argued with her mother the night before the murder. Orangeburg County Sheriff Larry Williams has stated that “We believe this is a direct response [to the argument] from Ms. Duley. I believe she was just fed up with her mother telling her she couldn’t take care of the children and she wasn’t taking care of her children and she just wanted to be free.” Williams also said that Shaquan’s mother “was a very, I guess, firm individual. … She often talked with her daughter about, I guess, maybe being more of a mother or being more reliable.”

Sources

• Lisa Flam. “SC Sheriff: Mother Has Confessed in Toddler Deaths” — AOL News, August 17, 2010
• “Sheriff: Woman suffocated sons before submerging bodies in car” — CNN, August 17, 2010

US officials said Monday that an American, Aijalon Mahli Gomes, sentenced to hard labor in North Korea was visited by a US consular official and two American doctors.

“We requested permission to visit Mr. Gomes. That permission from the North Korean government was granted,” said U.S. State Department spokesman Philip Crowley. Crowley also said that “We requested permission to bring Mr. Gomes home. Unfortunately, he remains in North Korea.”

North Korea said that Gomes was hospitalized after attempting suicide. Gomes was arrested by North Korean authorities and sentenced to eight years of hard labor in January after the 31 year-old man alledgedly attempted to cross the border with China.

Sources

• Brian Walker. “U.S. officials visit American held in North Korea” — CNN, August 17, 2010
• Agence France-Presse. “US medical team visited American held in N.Korea: official” — Google News, August 16, 2010

Related news

• “US prisoner in North Korea ‘attempts suicide'” — Wikinews, July 10, 2010

American car company General Motors (GM) said Tuesday that it will recall 243,000 crossover vehicles due to faulty seat belts. The crossovers recalled include the Saturn Outlook, Buick Enclave, GMC Acadia and Chevrolet Traverse. The damage to the seat belts could happen after the second row seats in the car-based SUVs are returned to a upright position after being folded. The damage causes the seat belt to feel correctly latched when it is possibly not.

Sources

• “GM recalls 243,000 crossover vehicles” — United Press International, August 17, 2010
• Nick Bunkley. “G.M. Recalls 243,000 Crossover Vehicles for Seat Belt Problem” — The New York Times, August 17, 2010

Friday, March 30, 2007

At Wilfrid Laurier University in Waterloo, Ontario, Canada, students are finding that popular MP3 players, such as Apple’s iPod, are very convenient devices for listening to music at the gym, while traveling on foot, and in the car.

In a recent ad-hoc survey conducted by Wikinews contributor Darren Mar, 150 students were randomly pulled aside in the hallways of the university, and asked if they own an MP3 player. 94 of the 150 students (62.66%) did in fact own MP3 devices, most of who were found to be carrying it on them when questioned. There was one simple follow up question for those who had a player: “If it were possible to have complete and safe control of the device on the steering wheel of a car, would you rather listen to your device, or the radio?” There were three answers possible, yes, no or both. Of the 94, 78 (82.98%) said yes, eleven (11.70%) said no, and five (5.32%) said both. The reporting took place primarily on March 16, 2007. The reasons for those who would listen to their device were commercial free music, personalized choice of music, and complete control of what you are listening to.

This study was motivated by the new design of 2006+ model cars. Many are being built with auxiliary jacks for the stock radio, allowing the driver to easily connect any audio playing device to the car’s sound system with a simple 3.5mm plug. What’s more, cars in the upper price echelon are being built with (1) a custom made area in the dash for MP3 players (iPod’s being the most popular), and (2) implementing audio device control right onto the steering wheel. A good example of this is the Ford Fusion or the 2007 Lexus IS250: “The centre console input port allows an iPod, MP3 or Windows Media Audio player to be plugged into the IS audio system.”

Tuesday, June 12, 2007

North America’s largest outdoor dog festival came back to Toronto last weekend for its fifth year. It ran from the 9th of June to the 10th of June at Toronto’s historical St. Lawrence Market. A Wikinews reporter was there on Sunday to report on some of the events that happened on the last day.

The “Woofstock” dog festival attracted as many as 140,000 people with their dogs. The festival had tons of accessories, sold under tents, to buy for dogs; food, toys, designer clothes, and more. About 400 vendors and exhibitors were there to promote their products, which also gave private dog companies or groups a chance to show their new products. The local SPCA and some animal rescues were under tents answering questions from visitors. While walking, all visitors could see the CN Tower and other very tall buildings.

One of the local TV stations, Citytv, was there. They hosted a live event at the show which was broadcast on TV. People came up on the stage and asked questions regarding their dogs and the host and co-host answered them.

A man, who called himself the “Chalk Master”, drew two pictures on pavement with chalk. He did it for free but donations were welcome. One was a picture of a girl’s head beside a dog’s head, and another with a wolf.

“Hello Humans. I’ve been invited here to provide your eyeball(s), with some pretty colours. I don’t get paid as I work this weekend strictly for tips… so, if you like what you see please make a DONATION. If you don’t like it simply reach into the pocket of the person next to you and give me their money. CHALK MASTER.”

A contest called “Canada’s top dog” had its own tent with a professional photographer taking pictures of dogs behind a white screen; the winning photo is to be published on the cover of “Puppy and dog basics” magazine.

Large “Gourmet” dog bones were also served from a cart and table.

Next year’s festival is expected to be bigger and better with even more attractions.