Why is medicinal chemistry important?

by

Jamie Francis

Put simply, medicinal chemistry also known as pharmaceutical chemistry is the discipline that keeps the future of drug discovery and development alive and kicking. Since the world began, man has found ways to keep himself safe, warm, nourished and well, and in modern history, the last of these has become the responsibility of scientists, laboratories, research organisations and pharmaceutical companies.

The drug development process is a lengthy and highly complex one; it can take several years for an idea, synthetic component or naturally occurring medicinal agent to become a drug that can be clinically trialled, rolled out across the country and administered by doctors, nurses and dentists to patients. In most cases the cost of developing a drug to treat a particular disease has to be weighed up alongside the beneficial effects it hopes to offer. Funding for research and the drug development process is therefore something that many high profile charities fundraise for and which pharmaceutical and healthcare companies have to budget for in their yearly targets.

[youtube]http://www.youtube.com/watch?v=4h2oxmMKlMU[/youtube]

Cost aside, medicinal chemistry is vitally important to the treatment of diseases and without it, statistics on the recovery from certain serious illnesses and overall life expectancy could quite easily drop dramatically – it really is as important as that. Without medicinal chemistry, the discovery of new and more effective drugs would simply not happen at the rate it does now, and in many cases it wouldn t happen at all, and this is quite frankly a scary prospect for the human race.

Its importance is reflected in the sheer amount of research material and resources available online and the regular demand for this. For those heads of research, directors of chemistry, and others working in the drug development process, information gathered about particular components, new discoveries, and so on, these resources are an essential way to gather information that has already been scientifically verified, thus saving a great deal of repetition and expense.

For those people, the volume of online resources is essential in carrying out vital work and discovering new drugs to keep the human race healthy in as many cases as possible. These resources are available to all who need them and often form the backbone of a revolutionary medicinal discovery.

Find out more about the importance of

medicinal chemistry

and the

drug development process

online and get access to vital resources and publications to help you with your research.

Article Source:

ArticleRich.com

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2008 COMPUTEX Taipei: Three awards, One target

Monday, June 23, 2008

2008 COMPUTEX Taipei, the largest trade fair since its inception in 1982, featured several seminars and forums, expansions on show spaces to TWTC Nangang, great transformations for theme pavilions, and WiMAX Taipei Expo, mainly promoted by Taipei Computer Association (TCA). Besides of ICT industry, “design” progressively became the critical factor for the future of the other industries. To promote innovative “Made In Taiwan” products, pavilions from “Best Choice of COMPUTEX”, “Taiwan Excellence Awards”, and newly-set “Design and Innovation (d & i) Award of COMPUTEX”, demonstrated the power of Taiwan’s designs in 2008 COMPUTEX Taipei.

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Bobby Robson recovering from operation

Wednesday, August 23, 2006

Earlier today former England-manager Bobby Robson underwent surgery to remove a tumour from his brain.

A statement was made saying the surgery went “very well”, and that the tumour has been completely removed.

The Football Association of Ireland hopes that Sir Bobby Robson will be able to resume his duties as a consultant for the Republic of Ireland team for the games against Cyprus and the Czech Republic in early October.

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Scotland denies bail to terminally ill man convicted of Lockerbie bombing

Saturday, November 15, 2008

Scotland has refused bail to the Libyan man convicted of the bombing of Pan Am Flight 103 despite his terminal cancer, as he can receive treatment in prison. Abdelbaset Ali Mohmed Al-Megrahi was jailed in 2001 for the 1988 bombing of the transatlantic airliner, killing 270 people, but is seeking to have his conviction overturned.

Minutes after Edinburgh’s Appeals Court rejected bail on compassionate grounds Jim Swire, spokesman for the victim’s families who lost his daughter in the disaster, complained about the ruling. “It has never been a goal of our group to seek revenge,” said a lawyer outside the court reading from his statement. “The refusal of a return to his family for a dying man whose verdict is not even yet secure looks uncomfortably like either an aspect of revenge — or perhaps timidity.”

Al-Megrahi, a former intelligence officer, is 54 and serving a minimum of 27 years for the bombing. He has advanced prostate cancer which is spreading through his body. His request for bail was rejected by Lord Hamilton, Scotland’s head judge, who said that as doctors say he could live a few more years he should not be released unless and until after his appeal succeeds or his condition worsens.

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Some other doctors give his time as just months, as the cancer has reached his bones. Hamilton however said that palliative hormone treatment could prolong his life. Hamilton also said Al-Megrahi was not suffering “material pain or disability”.

The Scottish Criminal Cases Review Commission ruled last year that the conviction may be a miscarriage of justice. It said there was significant doubts to be raised over several key pieces of evidence in the original trial.

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Auto Dealers Are Using Social Media To Reach Out And Manage New Consumers

Auto Dealers are Using Social Media to Reach Out and Manage New Consumers

by

Lakeelsinoreford.com

As the effectiveness of traditional advertising methods (traditional methods include print advertising and TV advertising) are called into question more and more dealerships are turning to digital methods for promoting their dealerships. One of those digital methods is the use of social media sites. With so many social media networks out there it can be easy for dealerships to get overwhelmed by the prospect of creating a social media strategy. But ignoring the power of social media to reach out to consumers is a mistake dealerships can’t afford to make.

[youtube]http://www.youtube.com/watch?v=oH87MtZuBcY[/youtube]

Connect With Your Consumers A powerful aspect of social media is the ability to connect with consumers. An important thing to remember when using social media to connect with consumers is that consumers are not looking for things to be sold while on these networks. Rather they are looking for deeper relationships and connections with the brands they connect with. While dealerships are connecting with consumers on social media networks, it is important to keep in mind who their audience is. An article in business2community.com suggests that while reaching out to consumers, the best way for dealerships to connect is to first connect with their current consumers. These consumers have already purchased a good or service from them and are already familiar with their brand. Once they have reached out to current consumers, then it is time to reach out to potential consumers. While connecting with potential consumers, it is important to remember that the quality of followers is better than quantity. A dealership reaching out to three local consumers who will interact with and, in turn hopefully promote their brand are better than 1,000 followers who like or follow a dealer’s social media page and do nothing else. Business2Community also suggests that if dealerships are having trouble gaining new followers, they should offer small incentives for consumers who engage with their social media page or pages. This is a simple yet effective tactic that allows dealerships to gain new followers who will actively engage with their brand. Which Site is Right For Your Dealership? Not all social media sites are created equally, and as such it is not as important for dealerships to be on every social media site. If a dealer’s social media strategy is to foster an online community where people can have a common place to talk about the dealership and share experiences, then Facebook is the place they’ll want to be. If a dealership simply wants to push content and information about their dealership, while fostering interactions with said content, then Twitter is their site. If a dealer wants to post photos of their inventory for their consumers to see, then Pinterest – a mostly visual social media network – is their answer. Though, the best social media strategies for dealerships should include the use of some sort of combination of social media sites, which are used to reach out to consumers. According to Mongoose Metrics, 22% of dealerships already use both Facebook and Twitter in their social media strategies. Instant Communication Quite possibly the most powerful aspect of social media is the capability of instant communication. No longer do dealerships have to wait for their ads to show up in local newspapers or TV ads to promote upcoming sales or promotions. Now they can instantaneously update their fans or followers about upcoming events and promotions. It is this instant communication that is so essential to dealerships and their social media efforts. Instead of sending direct mail pieces that may or may not be opened, dealers have a way to reach out to consumers, and track the success of their messages. This is most likely the reason why according to a report done by CNW Research, around 41% of dealers in the U.S. use social media sites like Facebook to promote their dealerships. Social media is a powerful tool that dealerships can no longer ignore. With their streamlined ability to reach out to consumers and promote brands, social media strategies should be a part of every dealership’s digital marketing efforts.

Lake Elsinore Ford sells new & pre-owned Ford vehicles, service & parts. We also house a large variety of pre-owned inventory from other manufacturers to meet the needs of our Riverside County area customers. IF you are searching for Ford dealers using keywords

Lake Elsinore Ford

or

Ford Lake Elsinore

, come visit us in Lake Elsinore today!

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Auto Dealers are Using Social Media to Reach Out and Manage New Consumers

News briefs:February 04, 2008

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News briefs:February 04, 2008
Author: Admin

29 Mar

[edit]

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Spelbound declared winner of Britain’s Got Talent 2010

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Spelbound declared winner of Britain’s Got Talent 2010
Author: Admin

29 Mar

Monday, June 7, 2010

An acrobatic group known by the name of Spelbound has been declared as the winner of Britain’s Got Talent 2010, a televised variety talent show competition broadcast on ITV in the United Kingdom. As the winning act of the show, Spelbound have won £100,000 (US$144,580, €120,313, A$175,079) and a place at The Royal Variety Performance, an annual gala evening that is attended by senior members of the British Royal Family.

In no particular order, the top three acts were revealed to be two dancers known by their stage name of Twist and Pulse, gymnastic group Spelbound and Kieran Gaffney, whose act involves playing on the drum kit. After Kieran Gaffney was revealed to be in third place, Anthony McPartlin, who hosts Britain’s Got Talent with Declan Donnelly, said to Kieran: “Well done Kieran. Kieran, you’re a star, you came back, you got all the way to the final. I know you’ve loved this. You’ve loved this, haven’t you?” In response to this, Kieran Gaffney stated: “Thank you very much. Thank you, everyone for supporting me. Thank you.”

Shortly afterwards, on the episode that was broadcast live on ITV1 on Saturday, Anthony announced: “After tens of thousands of auditons, five semi-finals and an amazing final, this…this is it. One of you is about to walk away with £100,000 and a place at this year’s Royal Variety Performance. The winner of Britain’s Got Talent 2010 is…Spelbound!” Glen Murphy from Twist and Pulse commented about finishing in second place, stating: “Yeah, it’s amazing. I can’t even believe it. I can’t believe it at all.”

Alex Uttley, a 24-year-old member of Spelbound, commented on the gymnastic group’s victory, commenting: “Oh, my god. This is unbelieveable. We just want to say thank you to everyone out there. It just shows that all our hard work has paid off.” One of the coaches of Spelbound, named Neil Griffiths, stated about Spelbound: “Oh, they’ve worked so hard over the last few weeks. Um, since the semi-final, we…we really had to pull out the stops to try and up the game. They’ve not known they’ve worked in the gym from six in the morning till twelve…twelve o’clock of the night. I couldn’t have asked for more. Um, it’s a team of coaches. I don’t take all the credit myself. There’s, uh, two people up there that know who they are who’ve been fantastic.”

Spelbound consists of 24-year-old Alex Uttley, Nicholas Illingworth, aged 24, Adam Buckingham, aged 21, 20-year-old Adam McAssey, 19-year-old Douglas Fordyce, 18-year-old Edward Upcott, 18-year-old Leighanne Cowler, 17-year-old Katie Axten, 17-year-old Lauren Kemp, 15-year-old Jonathan Stranks, Abigail Ralph, aged 15, 13-year-old Hollianne Wood and Amy Mackenzie, aged 12. Bookmakers had previously predicted that Spelbound would be the most likely act to become the winner of the series.

The running order for the final started with Twist and Pulse. The second act to perform was Liam McNally, a 14-year-old singer. The running order subsequently continued with 40-year-old impressionist Paul Burling, singer Christopher Stone, aged 28, Tina & Chandi, a woman and dog dancing act, Connected, a five-piece singing group, Kieran Gaffney, aged 12, 22-year-old Tobias Mead, a dancer, 80-year-old singer Janey Cutler and Spelbound in that particular order.

Earlier on in the final, Britain’s Got Talent judge Amanda Holden has stated to Spelbound: “We are hosting the 2012 Olympics and I think ‘what a brilliant opening act’.” Fellow judge Piers Morgan also commented that “[t]he purpose of this show is to identify hidden great British talent. You are that act.” After Spelbound won in the final, another judge, named Simon Cowell, stated that “the right boys and girls won on the night” and that he could “only say on live TV that that was one of the most astonishing things I have ever seen. Seriously.”

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On The Net Texas Holdem Poker The Most Effective And Worst Moves A Beginner Can Make

Click Here To Know More About:

Submitted by: Arthuram Pruitt

– Try to remember to be individual use micro- limits to sharpen your skills via apply the most effective gamers will win dollars in these games.

4. Shell out attention to the board – Recognize the best hand you have or can make then gauge if you can win. A very good hand or a pretty great prospect of improving upon, usually means you should stay in the sport. If not, then fold and you have preserved your bankroll for the subsequent hand.

The Worst Moves a Novice Can Make:

one. Do not play just about any and just about every hand just because you are hoping to get lucky with the flop and win the hand.

– Indeed – At times you will get fortunate with this approach, on the other hand, that only offers an illusion that this tactic pays off when in reality you will a lot more than probable conclusion up shedding much more hands than you win and you will shed much more cash in the extensive operate – and it could be a ton of income lost!

[youtube]http://www.youtube.com/watch?v=vP0FpiADIE8[/youtube]

two. Not having any concept of what the greatest starting fingers are let by yourself an comprehending of “subsequent level” of best beginning hands.

3. Enjoying in the larger limit games right when you get started playing mainly because you imagine that if the stakes are greater you will win extra.

– Don’t get me mistaken if you are an experienced player with an exceptional track document then the above is probably correct, but it is one particular of the worst moves a starter could make.

– The greater stakes game titles will also have more robust levels of competition because the players are typically a great deal additional expert – so if you play too many fingers you will conclusion up losing a whole lot of money.

four. Not mastering to examine the board will indicate far more hands and income lost

– It’s easy definitely if you don’t pay consideration and recognize the board how will you know if you can win or if you have a possibility of bettering?

To sum up if you are shopping to play on the web then you want to stick to the best commencing fingers, pay focus to the board and get started out in micro-limit games – with persistence and practical knowledge you will find out to examine your opponents improved and you are significantly much more possible to make income with poker on line!

Welcome to the fifth in my Texas Holdem Poker Tactic Sequence, focusing on no restrict Texas Holdem poker tournament play and involved approaches. In this article, we’ll examine beginning hand selections.

It may possibly appear obvious, but determining which commencing fingers to play, and which ones to skip enjoying, is 1 of the most crucial Texas Holdem poker selections you’ll make. Deciding which beginning fingers to play begins by accounting for numerous components:

* Beginning Hand “groups” (Sklansky designed some good ideas in his classic “Theory of Poker” e-book by David Sklansky)

* Your table situation

* Selection of gamers at the table

* Chip situation

Sklansky at first proposed some Texas Holdem poker starting hand groups, which turned out to be really useful as basic pointers. Under you will find a “modified” (enhanced) version of the Sklansky beginning hands table.

About the Author: Texas Holdem Poker Tournament Approach – Starting Hands

texas-holdem-e.com/

Source:

isnare.com

Permanent Link:

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Wikinews interviews Frank Moore, independent candidate for US President

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Wikinews interviews Frank Moore, independent candidate for US President
Author: Admin

27 Mar

Saturday, March 1, 2008

While nearly all coverage of the 2008 Presidential election has focused on the Democratic and Republican candidates, the race for the White House also includes independents and third party candidates. These parties represent a variety of views that may not be acknowledged by the major party platforms.

Wikinews has impartially reached out to these candidates, throughout the campaign. We now interview independent Presidential candidate Frank Moore, a performance artist.

Retrieved from “https://en.wikinews.org/w/index.php?title=Wikinews_interviews_Frank_Moore,_independent_candidate_for_US_President&oldid=2185149”

Man charged with attempted murder in £40 million London jewel heist

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Man charged with attempted murder in £40 million London jewel heist
Author: Admin

27 Mar

Sunday, September 6, 2009

24-year-old Aman Kassaye, of no fixed abode, is to face a charge of attempted murder for his alleged role in an armed robbery that netted £40 million ($65 million) worth of jewelry from a London store.

Kassaye is the seventh man to be charged, and is also facing prosecution for conspiracy to rob the Graff store in New Bond Street, false imprisonment, and using a handgun to resist arrest. He will appear at Wimbledon magistrates court on Monday.

The other six men have already been remanded in custody until October 23, when they will appear at Kingston Crown Court. All are facing charges of conspiracy to rob, and two of them are also charged with a firearms offense.

43 diamond rings, watches, and bracelets were taken from the store. The theft occurred when two armed and suited men walked in and took an employee hostage. It has been reported they used prosthetic masks made from liquid latex but police have not confirmed this. Amateur footage also shows a shot was fired. No-one was injured.

The robbery is one of the biggest the United Kingdom has seen. After the crime a string of getaway vehicles was used, with police believing several more offenders assisted with this stage of the plan. Although The Telegraph claims no stolen property has yet been recovered, this is also unconfirmed by police.

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